Application of adhesives in the treatment of cartilage repair
Abstract From degeneration causing intervertebral disc issues to trauma‐induced meniscus tears, diverse factors can injure the different types of cartilage. This review highlights adhesives as a promising and rapidly implemented repair strategy. Compared to traditional techniques such as sutures and wires, adhesives offer several advantages. Importantly, they seamlessly connect with the injured tissue, deliver bioactive substances directly to the repair site, and potentially alleviate secondary problems like inflammation or degeneration. This review delves into the cutting‐edge advancements in adhesive technology, specifically focusing on their effectiveness in cartilage injury treatment and their underlying mechanisms. We begin by exploring the material characteristics of adhesives used in cartilage tissue, focusing on essential aspects like adhesion, biocompatibility, and degradability. Subsequently, we investigate the various types of adhesives currently employed in this context. Our discussion then moves to the unique role adhesives play in addressing different cartilage injuries. Finally, we acknowledge the challenges currently faced by this promising technology.
Authors
- Jian Yang (ORCID: https://orcid.org/0000-0003-2059-1912)
- Lei Fan (ORCID: https://orcid.org/0000-0003-0049-5819)
- Yongjian Sun (ORCID: https://orcid.org/0000-0002-9987-5821)
- Haoyang Feng (ORCID: https://orcid.org/0009-0005-3788-0077)
- Junji Li (ORCID: https://orcid.org/0000-0002-3104-6824)
- Huan Meng (ORCID: https://orcid.org/0000-0001-8844-3938)
- Pengfei Guan
- K. Kian Ang
Institutions
- AO Foundation (CH)
- Westlake University (CN)
- Third Affiliated Hospital of Southern Medical University (CN)
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Interdisciplinary medicine
- Published
- 2024-09-09
- DOI
- https://doi.org/10.1002/inmd.20240015
- Citations
- 17
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 7.99
Funders
- Natural Science Foundation of Guangdong Province
- Russian Science Foundation
- Southern Medical University