A pan‐cancer analysis of Wnt family member 7B in human cancers
We found significant upregulation of <i>Wnt7B</i> expression levels in the majority of cancer cases examined. Furthermore, <i>Wnt7B</i> can influence cancer prognosis by modulating the tumor microenvironment, immune cell infiltration, and tumor stemness, among other factors. Additionally, we examined the associations between anticancer drug sensitivity and <i>Wnt7B</i> expression, which could aid in the development of more precise clinical therapies.
Authors
- Zhi‐zhao Zhang
- Xiaowei Qi (ORCID: https://orcid.org/0000-0002-5876-4957)
- Yan Liang (ORCID: https://orcid.org/0000-0002-3002-5431)
- Cheng‐fang Wang
- Rui Wang
- Yan Wang
- Ni‐sha Wu
- Li Wang (ORCID: https://orcid.org/0000-0003-2068-7535)
- Yi Zhang (ORCID: https://orcid.org/0000-0001-6223-4724)
Institutions
- Army Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Southwest Hospital (CN)
- Guang’anmen Hospital (CN)
Publication Details
- Journal
- Cancer Innovation
- Published
- 2024-09-09
- DOI
- https://doi.org/10.1002/cai2.139
- Citations
- 5
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Southwest Hospital
- Centre Scientifique et Technique du Bâtiment