Interleukin‐6 induces cognitive impairment via toll‐like receptor 4 (TLR4)‐mediated neuroinflammation and neurodegeneration in mice with chronic kidney disease
These results suggest that IL-6 triggers TLR4 activation to induce neuroinflammation and neurodegeneration in CKD, ultimately culminate in cognitive impairment.
Authors
- Chenfei Zheng
- Yangping Shentu (ORCID: https://orcid.org/0009-0001-6171-0490)
- Yaozhe Ying (ORCID: https://orcid.org/0009-0008-4383-8774)
- Simin Ye
- Yongheng Bai (ORCID: https://orcid.org/0000-0003-3910-4731)
- Shuqing Ma (ORCID: https://orcid.org/0009-0000-9581-8216)
- Zongyuan Zhao
- Luhui Wang (ORCID: https://orcid.org/0000-0003-2253-8234)
- Chaosheng Chen
- Ying Zhou (ORCID: https://orcid.org/0000-0002-3336-5757)
- Yun Zhu
- Nan Jiang (ORCID: https://orcid.org/0000-0002-8423-7675)
- YunTing Wang
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- University of Houston (US)
Publication Details
- Journal
- Neuroprotection/Neuroprotection (Chichester, England. Print)
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/nep3.54
- Citations
- 2
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- Wenzhou Medical University
- Science and Technology Plan Project of Wenzhou, China
- Zhejiang Provincial Outstanding Youth Science Foundation