<i>Escherichia coli</i> alcohol dehydrogenase YahK is a protein that binds both iron and zinc
The dynamic binding of YahK to iron and zinc unveils its intricate regulatory mechanism as an alcohol dehydrogenase, thereby highlighting the possible physiological role of YahK in <i>E. coli</i> and its significance in governing cellular metabolic processes. This discovery provides a novel perspective for further investigating the specific impact of metal ion binding on YahK and <i>E. coli</i> cell metabolism.
Authors
- Xianxian Xu
- Shujuan Sun (ORCID: https://orcid.org/0000-0002-9141-9717)
- Beibei Li (ORCID: https://orcid.org/0009-0001-1006-9832)
- Liang Feng (ORCID: https://orcid.org/0000-0001-6171-2050)
- Guoqiang Tan (ORCID: https://orcid.org/0000-0001-6180-7308)
- Tiantian Peng
- YongGuang Zhou
Institutions
- Linyi University (CN)
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2024-09-10
- DOI
- https://doi.org/10.7717/peerj.18040
- Citations
- 2
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.62