Mitochondrial dysfunction and oxidative stress in selective fetal growth restriction
Findings collectively confirmed an exacerbation of oxidative stress within sFGR placentae, coinciding with mitochondrial dysfunction, compromised energy production, and ultimately the failure of compensatory mechanisms to restore energy balance, which may result from mutations in the mitochondrial genome and abnormal expression of epigenetic regulatory genes.
Authors
- Yan Bi (ORCID: https://orcid.org/0000-0003-3914-7854)
- Yucheng Hu (ORCID: https://orcid.org/0000-0002-3259-9746)
- Li Gao (ORCID: https://orcid.org/0000-0001-8762-6804)
- Shan Wang (ORCID: https://orcid.org/0000-0002-0273-8397)
- Jiawen Yang (ORCID: https://orcid.org/0000-0002-1360-655X)
- Yanlin Wang (ORCID: https://orcid.org/0000-0003-0995-2393)
- Yuhong Lin (ORCID: https://orcid.org/0009-0000-5267-665X)
Institutions
- International Peace Maternity & Child Health Hospital (CN)
Publication Details
- Journal
- Placenta
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1016/j.placenta.2024.09.005
- Citations
- 13
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 14.42