Proanthocyanidins alleviate Henoch‐Schönlein purpura by mitigating inflammation and oxidative stress through regulation of the TLR4/MyD88/NF‐κB pathway
PCs show promising therapeutic effects in HSP-like rats by mitigating inflammatory responses and oxidative damage, primarily through inhibiting the TLR4/MyD88/NF-κB pathway. These findings suggest PCs as a potential treatment avenue for HSP, warranting further investigation.
Authors
- Shihong Pan
- Jianqiao Zhong (ORCID: https://orcid.org/0000-0002-0482-1215)
- Dehai Xian (ORCID: https://orcid.org/0000-0003-1880-7091)
- Xiaolong Li (ORCID: https://orcid.org/0000-0001-6549-4089)
- Shuyi Zhang (ORCID: https://orcid.org/0000-0001-6582-5319)
- Xian Li (ORCID: https://orcid.org/0000-0002-9107-5096)
- Meng Wang (ORCID: https://orcid.org/0009-0004-4642-1983)
Institutions
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- Skin Research and Technology
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1111/srt.13921
- Citations
- 2
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Southwest Medical University