Mucor thriving on iron in beta thalassemia major: A case of rhino-orbital mucormycosis
Mucormycosis is a dreaded condition with high mortality rates noted in immunocompromised hosts. Though iron overload is a known risk factor, children with transfusion-dependent thalassemia have been rarely reported with invasive mucormycosis. We present an 8-year-old girl with transfusion-dependent thalassemia with hypersplenism and iron overload. She had invasive rhino-sino-orbital mucormycosis with a fatal outcome despite aggressive surgical and medical management.
Authors
- A. J. Kindo
- Dhaarani Jayaraman (ORCID: https://orcid.org/0000-0003-3210-6945)
- Padmasani Venkat Ramanan (ORCID: https://orcid.org/0000-0002-5911-3179)
- Naga Geetha Rani Mangam (ORCID: https://orcid.org/0000-0003-0646-1935)
- Julius Xavier Scott (ORCID: https://orcid.org/0000-0003-2390-7230)
- Harshavardhan Mahalingam (ORCID: https://orcid.org/0000-0002-6670-9915)
- Prasanna Kumar Saravanam (ORCID: https://orcid.org/0000-0002-8238-0419)
- Swati Narasimhan
- Banu Keerthana
- Manu Vidhya Harikumar
- Kumaraswamy Sudhakar
- Niranjan Ragavan
- T. K. Shruthi
Institutions
- Sri Ramachandra Institute of Higher Education and Research (IN)
Publication Details
- Journal
- Pediatric Hematology Oncology Journal
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1016/j.phoj.2024.09.003
- Citations
- 1
- Primary Topic
- Iron Metabolism and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.45