Half-Life and Clearance of Cardiac Troponin I and Troponin T in Humans
This novel method showed that the elimination half-life of cTnI and cTnT was 5 to 16 hours shorter than previously reported. This indicates a considerably longer duration of cardiomyocyte cTn release after MI than previously thought. Improved knowledge of timing of myocardial injury may call for changes in the management of MI and other disorders with myocardial injury.
Authors
- Kim Dalhoff (ORCID: https://orcid.org/0000-0002-5548-6381)
- Kristian Thygesen (ORCID: https://orcid.org/0000-0002-3674-1308)
- Shoaib Afzal (ORCID: https://orcid.org/0000-0002-1442-4694)
- Jesper Kjærgaard (ORCID: https://orcid.org/0000-0001-5244-0399)
- Mustafa Vakur Bor (ORCID: https://orcid.org/0000-0001-7596-8401)
- Jonas Henrik Kristensen (ORCID: https://orcid.org/0000-0002-2566-0502)
- Lene Holmvang (ORCID: https://orcid.org/0000-0002-0941-378X)
- Nicoline Jørgensen
- Julie Lyng Forman (ORCID: https://orcid.org/0000-0001-7368-0869)
- Rasmus Bo Hasselbalch
- Henning Bundgaard (ORCID: https://orcid.org/0000-0002-0563-7049)
- Nina Strandkjær (ORCID: https://orcid.org/0000-0002-8934-4541)
- Hasse Møller‐Sørensen (ORCID: https://orcid.org/0000-0001-8439-7743)
- Pia R. Kamstrup (ORCID: https://orcid.org/0000-0002-7627-6762)
- Morten Dahl (ORCID: https://orcid.org/0000-0002-6686-312X)
- Niklas Rye Jørgensen (ORCID: https://orcid.org/0000-0001-9624-5210)
- Line Rode (ORCID: https://orcid.org/0000-0002-9080-3389)
- Allan S. Jaffe (ORCID: https://orcid.org/0000-0003-1183-3959)
- Jens Christian Nilsson (ORCID: https://orcid.org/0000-0003-3928-4875)
- Ruth Frikke‐Schmidt (ORCID: https://orcid.org/0000-0003-4084-5027)
- Kasper Karmark Iversen (ORCID: https://orcid.org/0000-0003-0504-8487)
- Morten Østergaard
- Lia E. Bang
Institutions
- University of Copenhagen (DK)
- Mayo Clinic (US)
- Aarhus University (DK)
- Frederiksberg Hospital (DK)
- Herlev Hospital (DK)
- Aarhus University Hospital (DK)
- Copenhagen University Hospital (DK)
- Gentofte Hospital (DK)
- Rigshospitalet (DK)
- Zealand University Hospital (DK)
- Mayo Clinic in Arizona (US)
- Hospital South West Jutland (DK)
- Norwegian Womens Public Health Association (NO)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Circulation
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1161/circulationaha.123.066565
- Citations
- 24
- Primary Topic
- Acute Myocardial Infarction Research
- Type
- article
- Field-Weighted Citation Impact
- 9.65
Funders
- Gentofte Hospital