Elevated Serum IL-17A in Kawasaki Disease Patients Predicts Responsiveness to Intravenous Immunoglobulin Therapy

Serum IL-17A levels were remarkably elevated in IVIG-nonresponsive KD patients both before and after intervention. A serum IL-17A level (≥39.96 pg/mL) demonstrated good predictive profile for IVIG-nonresponsive KD, and combining IL-17A with CRP, WBC, and ALT improved diagnostic performance.

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Publication Details

Journal
International Archives of Allergy and Immunology
Published
2024-09-10
DOI
https://doi.org/10.1159/000540697
Citations
2
Primary Topic
Kawasaki Disease and Coronary Complications
Type
article
Field-Weighted Citation Impact
1.15
Controls
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article

Elevated Serum IL-17A in Kawasaki Disease Patients Predicts Responsiveness to Intravenous Immunoglobulin Therapy

Fang-Qi Hu, Yan Lü
2 citations
International Archives of Allergy and Immunology
Kawasaki Disease and Coronary Complications
1.15
article

Elevated Serum IL-17A in Kawasaki Disease Patients Predicts Responsiveness to Intravenous Immunoglobulin Therapy

Fang-Qi Hu, Yan Lü
article en
2 citations

Abstract

Serum IL-17A levels were remarkably elevated in IVIG-nonresponsive KD patients both before and after intervention. A serum IL-17A level (≥39.96 pg/mL) demonstrated good predictive profile for IVIG-nonresponsive KD, and combining IL-17A with CRP, WBC, and ALT improved diagnostic performance.

International Archives of Allergy and ImmunologyVol. 186(2)
Anqing City Hospital (CN)
Good health and well-being
Openalex Percentile: Top 21%
Kawasaki Disease and Coronary Complications
1.15
DOISourceOpenAlex
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Elevated Serum IL-17A in Kawasaki Disease Patients Predicts Responsiveness to Intravenous Immunoglobulin Therapy — Fang-Qi Hu, Yan Lü · International Archives of Allergy and Immunology (2024) | TGRS Research Map | TGRS