Prevalence of Cardiomyopathy in Patients with Type 1 Diabetes Mellitus

<b>Background:</b> Diabetic cardiac muscle disease or diabetic cardiomyopathy (DbCM) comprises a set of myocardial lesions that are not associated with coronary atherosclerosis or high blood pressure. It is characterized by fibrosis and hypertrophy, which ultimately results in heart failure. Diastolic dysfunction (DD) has been shown to be the first manifestation of diabetic cardiomyopathy. Currently, there are few studies on the prevalence of diabetic cardiomyopathy in adult patients diagnosed with type 1 diabetes mellitus (T1D). <b>Methods:</b> The study included 75 adult participants who underwent an echocardiogram. Data on their comorbidities were collected from their medical records and biochemical parameters were analyzed in blood and urine samples. <b>Results:</b> We found that the prevalence of DbCM in our T1D population was more than one-third (34%), which exceeded the prevalence reported in studies with adolescents and that reported in the population without diabetes. Also, we found that the probability of developing DD after 20 years of T1D diagnosis was 78%. <b>Conclusions:</b> Recommendations need to be issued in relation to diabetic cardiomyopathy to carry out secondary prevention in adult patients with T1D. More multicenter studies, which include a larger population, from different regions of the world need to be performed.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2024-09-10
DOI
https://doi.org/10.3390/jcm13185351
Citations
2
Primary Topic
Cardiovascular Function and Risk Factors
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article
Field-Weighted Citation Impact
0.80
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article

Prevalence of Cardiomyopathy in Patients with Type 1 Diabetes Mellitus

Oscar Orihuela, Aldo Ferreira‐Hermosillo, María del Pilar Sotelo-Gonzãlez, Eduardo Salif Luna-Ávila et al.
2 citations
Journal of Clinical Medicine
Cardiovascular Function and Risk Factors
0.80
article

Prevalence of Cardiomyopathy in Patients with Type 1 Diabetes Mellitus

Oscar Orihuela, Aldo Ferreira‐Hermosillo, María del Pilar Sotelo-Gonzãlez, Eduardo Salif Luna-Ávila, Andrés D. Litardo-Mosquera, Oscar Daniel Fabila-de la Cruz
article en
2 citations

Abstract

<b>Background:</b> Diabetic cardiac muscle disease or diabetic cardiomyopathy (DbCM) comprises a set of myocardial lesions that are not associated with coronary atherosclerosis or high blood pressure. It is characterized by fibrosis and hypertrophy, which ultimately results in heart failure. Diastolic dysfunction (DD) has been shown to be the first manifestation of diabetic cardiomyopathy. Currently, there are few studies on the prevalence of diabetic cardiomyopathy in adult patients diagnosed with type 1 diabetes mellitus (T1D). <b>Methods:</b> The study included 75 adult participants who underwent an echocardiogram. Data on their comorbidities were collected from their medical records and biochemical parameters were analyzed in blood and urine samples. <b>Results:</b> We found that the prevalence of DbCM in our T1D population was more than one-third (34%), which exceeded the prevalence reported in studies with adolescents and that reported in the population without diabetes. Also, we found that the probability of developing DD after 20 years of T1D diagnosis was 78%. <b>Conclusions:</b> Recommendations need to be issued in relation to diabetic cardiomyopathy to carry out secondary prevention in adult patients with T1D. More multicenter studies, which include a larger population, from different regions of the world need to be performed.

Journal of Clinical MedicineVol. 13(18)
Mexican Social Security Institute (MX), Centro Medico Nacional Siglo XXI (MX), Hospital de Especialidades (MX), Kennedy Clinic Hospital (EC), Universidad Nacional Autónoma de México (MX)
Good health and well-being
Openalex Percentile: Top 24%
Cardiovascular Function and Risk Factors
0.80
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Prevalence of Cardiomyopathy in Patients with Type 1 Diabetes Mellitus — Oscar Orihuela, Aldo Ferreira‐Hermosillo, et al. · Journal of Clinical Medicine (2024) | TGRS Research Map | TGRS