Update in diagnostic pathology of pituitary tumors - clinical and pathological perspective
Ndory hypofzy jsou bn intrakraniln tumory dospl populace. Naprost vtina ndor hypofzy je pedstavovna pituitrnmi neuroendokrinnmi tumory (PitNETy, dve adenomy), kter lze klasifikovat v zvislosti na linii diferenciace ndorovch bunk, je odr bunn populace normln hypofzy. Pslunost k rznm subpopulacm je zena jednm i vce transkripnmi faktory (Pit1, Tpit, SF1 a GATA3), kter reguluj mimo jin t hormonln produkci v normlnch i ndorovch bukch hypofzy. Tento pehledov lnek v krtkosti z perspektivy diagnostick patologie shrnuje novinky ve WHO klasifikaci PitNET a dle se zabv vzcnjmi lzemi hypofzy, jmenovit kraniofaryngiomy, pituicytomy a sekundrnmi ndory sellrn oblasti.
Authors
- David Netuka (ORCID: https://orcid.org/0000-0001-8609-4789)
- Filip Gabalec (ORCID: https://orcid.org/0000-0002-7053-3369)
- Mikuláš Kosák (ORCID: https://orcid.org/0000-0001-5947-5340)
- Jiří Soukup
Publication Details
- Journal
- Neurologie pro praxi
- Published
- 2024-09-10
- DOI
- https://doi.org/10.36290/neu.2024.027
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00