Multisample lipidomic profiles of irritable bowel syndrome and irritable bowel syndrome-like symptoms in patients with inflammatory bowel disease: new insight into the recognition of the same symptoms in different diseases
This study revealed a comprehensive lipid composition pattern between IBS-D patients and UCR-IBS patients. We found several distinctive lipids involved in alpha-linolenic acid metabolism, reflecting an imbalance in the omega-6/omega-3 fatty acid ratio. Compared to mucosa and serum samples, fecal samples might have more advantages in lipidomics studies due to the convenience of sample collection and effectiveness in reflecting metabolic information.
Authors
- Miao Wang (ORCID: https://orcid.org/0000-0003-2189-1204)
- Shiyu Du (ORCID: https://orcid.org/0000-0002-5482-2240)
- Bing Shao (ORCID: https://orcid.org/0000-0001-5631-6889)
- Hui Li (ORCID: https://orcid.org/0000-0002-7245-9609)
- Yanli Zhang (ORCID: https://orcid.org/0000-0001-8173-2024)
- Guorong Chen
- Huiting Zhu (ORCID: https://orcid.org/0000-0002-4335-9537)
- Junhai Zhang (ORCID: https://orcid.org/0000-0002-3514-0471)
- Huifen Wang (ORCID: https://orcid.org/0000-0002-5888-9899)
- Xuan Wu
- Shijie Sun
- Kemin Li
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China-Japan Friendship Hospital (CN)
- Peking Union Medical College Hospital (CN)
- Beijing Center for Disease Prevention and Control (CN)
Publication Details
- Journal
- Journal of Gastroenterology
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1007/s00535-024-02148-1
- Citations
- 4
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 1.87