A Mathematical Model of Interstitial Fluid Flow and Retinal Tissue Deformation in Macular Edema
Despite inherent simplifications and uncertainties in parameter values, this study represents a step toward understanding the pathophysiology of EME. The findings provide insights into the mechanisms underlying fluid dynamics in the retina and fluid accumulation in the foveal region, showing that the specific conformation of Müller cells is likely to play a key role.
Authors
- Alessia Ruffini (ORCID: https://orcid.org/0000-0002-7690-5290)
- Mariia Dvoriashyna (ORCID: https://orcid.org/0000-0002-6057-1919)
- Rodolfo Repetto (ORCID: https://orcid.org/0000-0001-9332-5063)
- Andrea Govetto (ORCID: https://orcid.org/0000-0003-2192-810X)
- Mario Rosario Romano (ORCID: https://orcid.org/0000-0003-0348-0532)
Institutions
- Humanitas University (IT)
- University of Genoa (IT)
- University of Edinburgh (GB)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1167/iovs.65.11.19
- Citations
- 2
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.08