Size of lipid emulsion droplets influences metabolism in human CD4+ T cells
Size of lipid emulsion droplets significantly influences their uptake and subsequent metabolism in CD4<sup>+</sup> T cells. Our results highlight the potential for improved nutrient utilization with nanoemulsions in TPN formulations possibly leading to less adverse effects.
Authors
- Pakeerathan Srikanthan
- Martin Hersberger (ORCID: https://orcid.org/0000-0002-4472-329X)
- Eliana Lucchinetti (ORCID: https://orcid.org/0000-0003-3338-1279)
- Gregory Holtzhauer (ORCID: https://orcid.org/0000-0002-5560-2354)
- Gerhard Rogler (ORCID: https://orcid.org/0000-0002-1733-9188)
- Nazek Noureddine (ORCID: https://orcid.org/0000-0003-0308-5807)
- Stefanie D. Krämer (ORCID: https://orcid.org/0000-0002-0426-4340)
- Paulina Wawrzyniak (ORCID: https://orcid.org/0000-0001-9641-2103)
- Michael Zaugg (ORCID: https://orcid.org/0000-0002-2016-8973)
Institutions
- University of Alberta (CA)
- University of Zurich (CH)
- ETH Zurich (CH)
- University Hospital of Zurich (CH)
- University Children's Hospital Zurich (CH)
Publication Details
- Journal
- Biochemical and Biophysical Research Communications
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1016/j.bbrc.2024.150680
- Citations
- 2
- Primary Topic
- Clinical Nutrition and Gastroenterology
- Type
- article
- Field-Weighted Citation Impact
- 0.62
Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung