Photoredox-Catalyzed Difunctionalization of Alkenes with Sulfilimines
Herein, we disclose a facile photoinduced difunctionalization of alkenes, enabling the synthesis of valuable β-amino alcohols, β-amino ethers, and 1,2-diamines with diverse nucleophiles. The protocol relies on the use of readily accessible dibenzothiophene-based sulfilimines as novel <i>N</i>-radical precursors, showcasing high functional-group tolerance and exclusive regioselectivity under mild reaction conditions.
Authors
- Ai‐Hong Yang (ORCID: https://orcid.org/0000-0002-0827-655X)
- Yan Ji (ORCID: https://orcid.org/0000-0002-1363-6513)
- Penghao Jia (ORCID: https://orcid.org/0000-0001-5402-1403)
- Zhe Jin
- Tingwei Yu
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1021/acs.orglett.4c02971
- Citations
- 9
- Primary Topic
- Synthesis and Catalytic Reactions
- Type
- article
- Field-Weighted Citation Impact
- 2.25
Funders
- National Natural Science Foundation of China
- Tianjin Municipal Education Commission