Genetically predicted hypothyroidism, thyroid hormone treatment, and the risk of cardiovascular diseases: a mendelian randomization study
The results of our study suggest a positive association between hypothyroidism and myocardial infarction and highlight the potential effects of levothyroxine treatment, the main thyroid hormone replacement therapy approach, on increasing the risk of experiencing myocardial infarction and heart failure.
Authors
- Chengjian Guan (ORCID: https://orcid.org/0000-0002-8002-5499)
- Hangtian Yu (ORCID: https://orcid.org/0009-0007-9760-241X)
- Shuchen Chen (ORCID: https://orcid.org/0000-0002-3316-9908)
- Jingchao Lu (ORCID: https://orcid.org/0000-0002-6946-0086)
- Bing Xiao (ORCID: https://orcid.org/0000-0001-9526-4575)
- Yan Zhao (ORCID: https://orcid.org/0000-0001-8698-6146)
- Shuaidan Zhang
- Angwei Gong
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1186/s12872-024-04132-2
- Citations
- 3
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.65