HBx promotes tumorigenicity through RRM2-mediated autophagy in hepatocellular carcinoma
Therefore, we hypothesised that RRM2 is a potential downstream target of HBx-induced hepatocarcinogenesis, and mining the oncogenic mechanism of RRM2 is significant in exploring the preventive treatment of HBV-related HCC.
Authors
- Yun Song (ORCID: https://orcid.org/0000-0002-7168-8274)
- Zikai Geng (ORCID: https://orcid.org/0000-0002-0601-365X)
- Tianye He
- Bin Wang (ORCID: https://orcid.org/0000-0002-4869-1352)
- Jian Wu (ORCID: https://orcid.org/0000-0002-2333-1000)
- Yaqun Li
- Furan Wang
Institutions
- Shandong University of Aeronautics (CN)
- Fudan University (CN)
- Fudan University Shanghai Cancer Center (CN)
- Pfizer (China) (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Cell & Bioscience
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1186/s13578-024-01298-2
- Citations
- 4
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.55
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province
- Wu Jieping Medical Foundation