Haploinsufficiency of intraflagellar transport protein 172 causes autism-like behavioral phenotypes in mice through BDNF
Our data suggest that Ift172 per se drives neurotrophic effects and, when defective, could cause neurodevelopmental disorders reminiscent of autism-like disorders.
Authors
- Shilin Luo (ORCID: https://orcid.org/0000-0002-6773-7790)
- Nanxi Zheng
- Ling Hu (ORCID: https://orcid.org/0000-0003-3104-8050)
- Colin McCaig (ORCID: https://orcid.org/0000-0001-5151-8254)
- Yu‐Qiang Ding (ORCID: https://orcid.org/0000-0003-1202-4635)
- Mingyu Li (ORCID: https://orcid.org/0000-0003-1217-2929)
- Bing Lang (ORCID: https://orcid.org/0000-0002-0076-2094)
- Xin Zhang (ORCID: https://orcid.org/0000-0001-7975-9965)
- Muzhi Huang
Institutions
- Fujian Medical University (CN)
- Central South University (CN)
- University of Aberdeen (GB)
- Fudan University (CN)
- National Clinical Research (US)
- Second Xiangya Hospital of Central South University (CN)
- Xiangya Hospital Central South University (CN)
- Zhejiang University of Technology (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1016/j.jare.2024.08.041
- Citations
- 2
- Primary Topic
- Genetic and Kidney Cyst Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.10
Funders
- National Natural Science Foundation of China