Splenectomy as a Risk Factor for Graft Rejection Following Endothelial Transplantation: Retrospective Study

Our results suggest that splenectomy has no major effect on the outcome following DMEK. Subsequent, ACAID may not be the main reason for the favorable immunological outcomes in DMEK, or the camero-splenic axis may be subordinate in humans. However, we only included 16 patients who underwent splenectomy, so it might be possible that we missed a minor effect.

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Publication Details

Journal
Interactive Journal of Medical Research
Published
2024-09-10
DOI
https://doi.org/10.2196/50106
Primary Topic
Corneal surgery and disorders
Type
article
Field-Weighted Citation Impact
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article

Splenectomy as a Risk Factor for Graft Rejection Following Endothelial Transplantation: Retrospective Study

Thomas Reinhard, Daniel Böhringer, Philip Maier, Thabo Lapp et al.
Interactive Journal of Medical Research
Corneal surgery and disorders
article

Splenectomy as a Risk Factor for Graft Rejection Following Endothelial Transplantation: Retrospective Study

Thomas Reinhard, Daniel Böhringer, Philip Maier, Thabo Lapp, Paola Kammrath Betancor
article en

Abstract

Our results suggest that splenectomy has no major effect on the outcome following DMEK. Subsequent, ACAID may not be the main reason for the favorable immunological outcomes in DMEK, or the camero-splenic axis may be subordinate in humans. However, we only included 16 patients who underwent splenectomy, so it might be possible that we missed a minor effect.

Interactive Journal of Medical ResearchVol. 13
University of Freiburg (DE), University Medical Center Freiburg (DE), St. Franziskus Hospital (DE)
Good health and well-being
Openalex Percentile: Top 75%
Corneal surgery and disorders
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