Different ethanol exposure durations affect cytochrome P450 2E1-mediated sevoflurane metabolism in rat liver
Ethanol exposure increased both the expression and enzymatic activity of CYP2E1, consequently enhancing the metabolism of sevoflurane.
Authors
- Wei Jiang (ORCID: https://orcid.org/0000-0003-0818-8784)
- Youbo Zuo (ORCID: https://orcid.org/0009-0007-8279-1668)
- Rui Cao (ORCID: https://orcid.org/0000-0001-9295-8299)
- Min Zhang (ORCID: https://orcid.org/0000-0002-0401-208X)
- Xinghao Wang (ORCID: https://orcid.org/0000-0001-8264-8537)
Institutions
- North Sichuan Medical University (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- BMC Anesthesiology
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1186/s12871-024-02704-5
- Citations
- 6
- Primary Topic
- Eicosanoids and Hypertension Pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 1.77