Easy Access to α-Ketothioamides via Oxidative Amidation of Bunte Salts Using Electrolysis or Hypervalent Iodine
Two new protocols leveraging electrochemical and hypervalent iodine-mediated synthesis of α-ketothioamides have been developed by using easily accessible and cost-effective Bunte salts and secondary amines. The methods are efficient, simple, and straightforward, and showcase the formation of C-N bonds across diverse substrates under ambient conditions.
Authors
- Neha Sharma Prabhakar
- Krishna Nand Singh (ORCID: https://orcid.org/0000-0001-9147-5463)
- Kaushal Kishor
Institutions
- Banaras Hindu University (IN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1021/acs.joc.4c01450
- Citations
- 5
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 1.25
Funders
- Department of Science and Technology, Ministry of Science and Technology, India
- University Grants Commission
- Science and Engineering Research Board