Ferulic acid ameliorates concanavalin A-induced hepatic fibrosis in mice via suppressing TGF-β/smad signaling

FA attenuated Con A-induced liver fibrosis through stimulating Nrf2 signaling, suppressing NF-kB, and inhibiting the TGF-β/smad3 signaling pathway. Thus FA can be considered as a promising therapy for combating liver fibrosis.

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Publication Details

Journal
Toxicology and Applied Pharmacology
Published
2024-09-10
DOI
https://doi.org/10.1016/j.taap.2024.117099
Citations
4
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
Field-Weighted Citation Impact
1.87

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article

Ferulic acid ameliorates concanavalin A-induced hepatic fibrosis in mice via suppressing TGF-β/smad signaling

Sara T. Elazab, Walter H. Hsu
4 citations
Toxicology and Applied Pharmacology
Drug-Induced Hepatotoxicity and Protection
1.87
article

Ferulic acid ameliorates concanavalin A-induced hepatic fibrosis in mice via suppressing TGF-β/smad signaling

Sara T. Elazab, Walter H. Hsu
article en
4 citations

Abstract

FA attenuated Con A-induced liver fibrosis through stimulating Nrf2 signaling, suppressing NF-kB, and inhibiting the TGF-β/smad3 signaling pathway. Thus FA can be considered as a promising therapy for combating liver fibrosis.

Toxicology and Applied PharmacologyVol. 492
Mansoura University (EG)
Mansoura University
Zero hunger
Openalex Percentile: Top 16%
Drug-Induced Hepatotoxicity and Protection
1.87
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