The Acylation of α-Carbonyl Sulfoxonium Ylides with N-Hydroxyphthalimide Esters
Abstract A new method for the synthesis of 1,3-dicarbonyl sulfoxonium ylides is described. This acylation reaction is carried out under mild conditions using inexpensive and bench-stable N-hydroxyphthalimide esters as acylating agents. The reactions proceed via a non-radical, transition-metal-free pathway, and the corresponding products are obtained in yields of up to 85%.
Authors
- Eduardo F. Mizobuchi
- Antonio C. B. Burtoloso (ORCID: https://orcid.org/0000-0003-2203-1556)
Institutions
- Universidade de São Paulo (BR)
Publication Details
- Journal
- Synthesis
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1055/a-2412-9549
- Citations
- 2
- Primary Topic
- Synthesis and Catalytic Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.50
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico