A New General, Mild Preparation of 2-Hydroxy-β-nitrostyrenes Starting from 2-Acetylsalicylaldehydes and Nitroalkanes via Domino Process
Abstract A new practical and improved preparation of 2-hydroxy-β-nitrostyrenes by reaction of nitroalkanes with acetylsalicylaldehydes, promoted by DBU in acetonitrile at 0 °C is reported. Under these conditions products were isolated in very good yields and as single E-diastereomers.
Authors
- Benedetta Bassetti (ORCID: https://orcid.org/0000-0001-5968-3676)
- Roberto Ballini (ORCID: https://orcid.org/0000-0002-5107-6449)
- Marino Petrini (ORCID: https://orcid.org/0000-0002-4941-5878)
- Alessandro Palmieri (ORCID: https://orcid.org/0000-0001-6599-3937)
- Lu Wang (ORCID: https://orcid.org/0000-0002-3918-3399)
Institutions
- Università di Camerino (IT)
Publication Details
- Journal
- Synthesis
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1055/a-2412-9635
- Citations
- 1
- Primary Topic
- Chemical Synthesis and Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.25