Impact of Chemotherapy on Circulating Lymphocyte Subsets in Lung Cancer Patients

Chemotherapy significantly affects lymphocyte subsets in a treatment-specific manner. The EarlyCycle group experienced a reduction in NK cell and an increase in T cell, suggesting a damage of innate immunity and an early shift towards adaptive immunity. The LateCycle group showed a substantial decrease in B cell, indicating a delayed effect on humoral immunity components.

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Publication Details

Journal
Cancer Management and Research
Published
2024-09-01
DOI
https://doi.org/10.2147/cmar.s475967
Citations
2
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
0.48
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article

Impact of Chemotherapy on Circulating Lymphocyte Subsets in Lung Cancer Patients

Xinyuan Zhang, Yanjun Wang, Wentao Wang, Wei Hong et al.
2 citations
Cancer Management and Research
Immune Cell Function and Interaction
0.48
article

Impact of Chemotherapy on Circulating Lymphocyte Subsets in Lung Cancer Patients

Xinyuan Zhang, Yanjun Wang, Wentao Wang, Wei Hong, Youkun Qi
article en
2 citations

Abstract

Chemotherapy significantly affects lymphocyte subsets in a treatment-specific manner. The EarlyCycle group experienced a reduction in NK cell and an increase in T cell, suggesting a damage of innate immunity and an early shift towards adaptive immunity. The LateCycle group showed a substantial decrease in B cell, indicating a delayed effect on humoral immunity components.

Cancer Management and ResearchVol. Volume 16
Fourth People's Hospital of Liaocheng (CN), Xian Yang Central Hospital (CN)
Good health and well-being
Openalex Percentile: Top 35%
Immune Cell Function and Interaction
0.48
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