Revealing genetic causality between blood-based biomarkers and major depression in east Asian ancestry
This study highlighted that BASO and LDLc have a causal effect on MD in East Asian ancestry. The pathological mechanisms of MD are related not only to inflammatory cytokines and oxidative stress but also to down regulation of <i>MFN2</i> expression and mitochondrial dysfunction.
Authors
- Zhengdong D. Zhang (ORCID: https://orcid.org/0000-0001-9508-1429)
- Chao Wang (ORCID: https://orcid.org/0000-0002-6251-7908)
- Dong‐Mei Wu
- Xiaoxiao Mo
- Qiuyi Pu
Institutions
- Ministry of Education (KR)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2024-09-10
- DOI
- https://doi.org/10.3389/fpsyt.2024.1424958
- Citations
- 2
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.10
Funders
- Nanjing Medical University