Combination of Youhua Kuijie Prescription and sulfasalazine can alleviate experimental colitis via IL-6/JAK2/STAT3 pathway
Our results showed that seven chemical components in YHKJ cooperate with SASP to interfere with activation of the IL-6/JAK2/STAT3 pathway, thus playing a role in the treatment of UC.
Authors
- Xiangyi Wang (ORCID: https://orcid.org/0000-0001-8634-3917)
- Hongwu Tao
- Cong Ren
- Lili Tang (ORCID: https://orcid.org/0000-0002-5269-3297)
- Yuedong Liu (ORCID: https://orcid.org/0009-0008-3909-2121)
- Ruijuan Luo
- Wenzhe Feng
- Y.‐Z. Shu
Institutions
- Liaoning University of Traditional Chinese Medicine (CN)
- Kaifeng University (CN)
- Kaifeng City Children's Hospital (CN)
- Affiliated Hospital of Shaanxi University of Chinese Medicine (CN)
- Affiliated Hospital of Liaoning University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-09-10
- DOI
- https://doi.org/10.3389/fphar.2024.1437503
- Citations
- 8
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 3.73
Funders
- National Natural Science Foundation of China