JARID2 activation by NFYA promotes stemness of triple-negative breast cancer cells through the PI3K/AKT pathway
NFYA promotes TNBC cell stemness by upregulating JARID2 expression and regulating the PI3K/AKT signaling pathway, suggesting JARID2 as a potential target for innovating drugs that target TNBC stem cells.
Authors
- Xiangmei Zhang (ORCID: https://orcid.org/0000-0003-3163-8237)
- Jianjie Li (ORCID: https://orcid.org/0000-0002-0143-3911)
- Xiangmin Ma
- Yanfang Wang (ORCID: https://orcid.org/0000-0002-8256-1180)
- Xueliang Liu (ORCID: https://orcid.org/0000-0001-9207-8742)
- Yunjiang Liu (ORCID: https://orcid.org/0000-0003-2485-1021)
Institutions
- Hebei Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Expert Review of Anticancer Therapy
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1080/14737140.2024.2394167
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.57