Five-year comparison of clinical and echocardiographic outcomes of pure aortic stenosis with pure aortic regurgitation or mixed aortic valve disease in the COMMENCE trial
Patients with Pure AR + MAVD demonstrated similar clinical safety and freedom from SVD at 5 years compared to those with Pure AS. There was a significant difference in LV reverse remodeling in the Pure AR + MAVD group compared to the Pure AS group at 5 years. These favorable outcomes in patients with AR may reinforce the need for treatment before irreversible changes occur.
Authors
- Eugene H. Blackstone (ORCID: https://orcid.org/0000-0001-9839-3567)
- Michael Andrew Borger (ORCID: https://orcid.org/0000-0003-1046-1364)
- Vinod H. Thourani (ORCID: https://orcid.org/0000-0002-9309-2623)
- Philippe Pîbarot (ORCID: https://orcid.org/0000-0002-3607-279X)
- John D. Puskas (ORCID: https://orcid.org/0000-0003-0459-4750)
- Joseph E. Bavaria (ORCID: https://orcid.org/0000-0001-7145-0453)
- Lars Georg Svensson (ORCID: https://orcid.org/0000-0002-5749-4588)
- Bartley P. Griffith (ORCID: https://orcid.org/0000-0003-3015-9322)
- Thomas M. Beaver (ORCID: https://orcid.org/0000-0003-1785-0119)
- David Heimansohn
- Anna Liza Antonio (ORCID: https://orcid.org/0009-0002-4221-9169)
Institutions
- University of Maryland, Baltimore (US)
- University of Maryland Medical Center (US)
- Cleveland Clinic (US)
- Emory University (US)
- St Vincent Hospital (US)
- Montreal Heart Institute (CA)
- University of Florida Health (US)
- Leipzig Heart Institute (DE)
- Université Laval (CA)
- University of Florida Health Science Center (US)
- Jefferson College (US)
- Edwards Lifesciences (Switzerland) (CH)
Publication Details
- Journal
- JTCVS Open
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1016/j.xjon.2024.08.020
- Citations
- 1
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.40
Funders
- Edwards Lifesciences