Multicohort Epigenome-Wide Association Study of All-Cause Cardiovascular Disease and Cancer Incidence
These results point to molecular pathways and potential treatments for precision prevention of CVD and cancer. Screening based on common epigenetic signatures of incident CVD and cancer may help identify patients with newly diagnosed CVD at increased cancer risk.
Authors
- Miguel Herreros-Martinez (ORCID: https://orcid.org/0000-0002-7533-0982)
- Jan Bressler (ORCID: https://orcid.org/0000-0001-6578-4772)
- M. Daniele Fallin (ORCID: https://orcid.org/0000-0002-9948-3908)
- Calen P. Ryan (ORCID: https://orcid.org/0000-0002-0550-7949)
- Marina Pollán (ORCID: https://orcid.org/0000-0002-4328-1565)
- Elizabeth A. Platz (ORCID: https://orcid.org/0000-0003-3676-8954)
- Carlos Manterola (ORCID: https://orcid.org/0000-0001-9213-2905)
- Miranda R. Jones (ORCID: https://orcid.org/0000-0003-4863-104X)
- Eric Boerwinkle (ORCID: https://orcid.org/0000-0001-8813-0544)
- Daniel W. Belsky (ORCID: https://orcid.org/0000-0001-5463-2212)
- Roby Joehanes (ORCID: https://orcid.org/0000-0001-5549-9054)
- Naisi Zhao (ORCID: https://orcid.org/0000-0002-0517-0709)
- Ángela L. Riffo‐Campos (ORCID: https://orcid.org/0000-0001-6300-3338)
- Dominique S. Michaud (ORCID: https://orcid.org/0000-0002-8107-3011)
- Jason G. Umans (ORCID: https://orcid.org/0000-0002-2746-3350)
- Daniel A Levy (ORCID: https://orcid.org/0000-0003-1843-8724)
- Shelley A. Cole (ORCID: https://orcid.org/0000-0002-2651-0127)
- Guillermo Ayala (ORCID: https://orcid.org/0000-0002-6231-2865)
- Karin Haack
- Ana Navas‐Acién (ORCID: https://orcid.org/0000-0001-9824-7797)
- Dorothy A. Rhoades (ORCID: https://orcid.org/0000-0002-4031-3576)
- Juan R. González (ORCID: https://orcid.org/0000-0003-3267-2146)
- Maria Tellez-Plaza
- Arce Domingo-Relloso
Institutions
- Universidad de La Frontera (CL)
- Tufts University (US)
- Texas Biomedical Research Institute (US)
- National Institutes of Health (US)
- Johns Hopkins University (US)
- Emory University (US)
- Universitat de València (ES)
- Baylor College of Medicine (US)
- Instituto de Salud Carlos III (ES)
- National Heart, Lung, and Blood Institute (US)
- Taiwan Centers for Disease Control (TW)
- INCLIVA Health Research Institute (ES)
- Baylor Genetics (US)
- Instituto Nacional de la Salud (ES)
- Sidney Kimmel Comprehensive Cancer Center (US)
- University of Oklahoma Health Sciences Center (US)
- Columbia University (US)
- MedStar Health (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- JACC CardioOncology
- Published
- 2024-09-10
- DOI
- https://doi.org/10.1016/j.jaccao.2024.07.014
- Citations
- 5
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Fundación Bancaria Caixa d'Estalvis i Pensions de Barcelona
- National Institutes of Health
- Centers for Disease Control and Prevention
- Instituto de Salud Carlos III
- National Heart, Lung, and Blood Institute
- National Cancer Institute
- National Institute of Environmental Health Sciences