Therapeutic effects of focused ultrasound on vulvar squamous intraepithelial lesions in rat

These results indicate that DMBA combined with mechanical irritation can induce vulvar squamous intraepithelial lesion in SD rats. Focused ultrasound can treat LSIL safely and effectively, prevent the progression of vulvar lesions, and improve the microenvironment of vulvar tissues by decreasing the localized expression of HIF-1α, VEGF, and mtp53 in rats.

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Publication Details

Journal
International Journal of Hyperthermia
Published
2024-09-10
DOI
https://doi.org/10.1080/02656736.2024.2401417
Primary Topic
Ultrasound and Hyperthermia Applications
Type
article
Field-Weighted Citation Impact
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article

Therapeutic effects of focused ultrasound on vulvar squamous intraepithelial lesions in rat

Huajun Tang, Chengzhi Li, Xi Wang, Yao Liu et al.
International Journal of Hyperthermia
Ultrasound and Hyperthermia Applications
article

Therapeutic effects of focused ultrasound on vulvar squamous intraepithelial lesions in rat

Huajun Tang, Chengzhi Li, Xi Wang, Yao Liu, Yijin Fan
article en

Abstract

These results indicate that DMBA combined with mechanical irritation can induce vulvar squamous intraepithelial lesion in SD rats. Focused ultrasound can treat LSIL safely and effectively, prevent the progression of vulvar lesions, and improve the microenvironment of vulvar tissues by decreasing the localized expression of HIF-1α, VEGF, and mtp53 in rats.

International Journal of HyperthermiaVol. 41(1)
The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Zero hunger
Openalex Percentile: Top 86%
Ultrasound and Hyperthermia Applications
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