Shikonin mitigates cyclophosphamide-induced cardiotoxicity in mice: the role of sirtuin-1, NLRP3 inflammasome, autophagy, and apoptosis
Shikonin may be used as an adjuvant to cyclophosphamide in cancer treatment, but further research is needed to investigate its effects on cardiotoxicity in distinct animal cancer models.
Authors
- Ahmed M. Kabel (ORCID: https://orcid.org/0000-0002-5101-8011)
- Mona Y. Alsheikh
- Hany M. Borg
- Fatemah A. Alherz (ORCID: https://orcid.org/0000-0002-6877-5158)
- Maaly A. Abd Elmaaboud
- Asmaa Saleh
Institutions
- Princess Nourah bint Abdulrahman University (SA)
- Kafrelsheikh University (EG)
- King Abdulaziz University (SA)
- Tanta University (EG)
Publication Details
- Journal
- Journal of Pharmacy and Pharmacology
- Published
- 2024-09-08
- DOI
- https://doi.org/10.1093/jpp/rgae119
- Citations
- 5
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Princess Nourah Bint Abdulrahman University