Comparative Evaluation of Diagnostic Performance: Standard E TB Feron ELISA vs QuantiFERON-TB Gold Plus for Latent Tuberculosis Infection Detection in Diverse Risk Groups in Bangladesh
We found a substantial agreement (Cohen's kappa of 0.71) between TBE and QFT-Plus in detecting LTBI across different groups, suggesting its potential as a cost-effective diagnostic tool. Implementation of TBE in routine clinical practice could increase accessibility to LTBI diagnosis, facilitating the timely initiation of preventative therapy, and leading to a reduction of active TB incidence.
Authors
- S. M. Mazidur Rahman (ORCID: https://orcid.org/0000-0003-2887-6250)
- Mohammad Khaja Mafij Uddin
- Maha Sultana Jabin
- Sayera Banu (ORCID: https://orcid.org/0000-0002-5121-1962)
- Jonathan Hoffmann
- Rumana Nasrin
- Stéphane Pouzol (ORCID: https://orcid.org/0000-0002-7875-2291)
- Jannatul Ferdous (ORCID: https://orcid.org/0000-0003-2390-9404)
- Ashabul Islam (ORCID: https://orcid.org/0009-0007-9479-2860)
- Tahmina Alam
- Salwa Khair
Institutions
- International Centre for Diarrhoeal Disease Research (BD)
- Fondation Mérieux (FR)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2147/idr.s475424
- Citations
- 7
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- Augustana College
- International Centre for Diarrhoeal Disease Research, Bangladesh
- Directorate for Biological Sciences
- University of California, San Diego