Single-Cell WGCNA Combined with Transcriptome Sequencing to Study the Molecular Mechanisms of Inflammation-Related Ferroptosis in Myocardial Ischemia-Reperfusion Injury

This study used single-cell transcriptomics technology to investigate the molecular mechanisms underpinning MIRI. Numerous important cell subtypes, gene regulatory networks, and disease-associated immune infiltration were also discovered. These findings provide new information and potential therapeutic targets for MIRI diagnosis and treatment.

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Publication Details

Journal
Journal of Inflammation Research
Published
2024-09-01
DOI
https://doi.org/10.2147/jir.s476456
Citations
5
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
1.17
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article

Single-Cell WGCNA Combined with Transcriptome Sequencing to Study the Molecular Mechanisms of Inflammation-Related Ferroptosis in Myocardial Ischemia-Reperfusion Injury

Zhaohe Huang, Zhuohua Zhang, Yan Liu, Da Huang
5 citations
Journal of Inflammation Research
Extracellular vesicles in disease
1.17
article

Single-Cell WGCNA Combined with Transcriptome Sequencing to Study the Molecular Mechanisms of Inflammation-Related Ferroptosis in Myocardial Ischemia-Reperfusion Injury

Zhaohe Huang, Zhuohua Zhang, Yan Liu, Da Huang
article en
5 citations

Abstract

This study used single-cell transcriptomics technology to investigate the molecular mechanisms underpinning MIRI. Numerous important cell subtypes, gene regulatory networks, and disease-associated immune infiltration were also discovered. These findings provide new information and potential therapeutic targets for MIRI diagnosis and treatment.

Journal of Inflammation ResearchVol. Volume 17
Affiliated Hospital of Youjiang Medical University for Nationalities (CN), First Affiliated Hospital of Jinan University (CN)
Good health and well-being
Openalex Percentile: Top 22%
Extracellular vesicles in disease
1.17
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