Human bone marrow mesenchymal stem cell-derived exosomes loaded with gemcitabine inhibit pancreatic cancer cell proliferation by enhancing apoptosis
Human bone marrow MSC-derived Exo-GEM have a potent cytotoxicity against human pancreatic cancer cells by enhancing their apoptosis, offering a promising drug delivery system for improving therapeutic outcomes.
Authors
- Yi Kong (ORCID: https://orcid.org/0000-0002-2329-7009)
- Yi Lü (ORCID: https://orcid.org/0000-0002-9655-7510)
- Zhe Wang (ORCID: https://orcid.org/0000-0002-3289-6134)
- Xicheng Wang (ORCID: https://orcid.org/0000-0001-6677-850X)
- Tie-Mei Chen
- Zu-Gui Tang
Institutions
- Guangdong Pharmaceutical University (CN)
Publication Details
- Journal
- World Journal of Gastrointestinal Oncology
- Published
- 2024-09-09
- DOI
- https://doi.org/10.4251/wjgo.v16.i9.4006
- Citations
- 11
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.57
Funders
- Department of Education of Guangdong Province
- Basic and Applied Basic Research Foundation of Guangdong Province