Comparative analysis of milk fat globule membrane proteins between porcine and human colostrum by a label‐free proteomics approach

This study aimed to investigate the similarities and differences in milk fat globule membrane (MFGM) proteins from porcine colostrum (PC) and human colostrum (HC) based on a label‐free proteomics approach. In total, 3901 and 4027 MFGM proteins were identified in PC and HC, respectively, including 3452 common proteins. Similar biological functions and pathways were found in two groups, whereas the quantities and types of MFGM proteins involved were different. This study compared the differences between MFGM proteins in PC and HC, effectively expanding the MFGM proteome and its bioinformatic database and providing new insights for the exploration of porcine milk.

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Publication Details

Journal
International Journal of Dairy Technology
Published
2024-09-08
DOI
https://doi.org/10.1111/1471-0307.13140
Citations
5
Primary Topic
Lipid metabolism and biosynthesis
Type
article
Field-Weighted Citation Impact
1.47

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article

Comparative analysis of milk fat globule membrane proteins between porcine and human colostrum by a label‐free proteomics approach

Huiwen Zhao, Xiqing Yue, Wanying Song, Zhenghan Zhang et al.
5 citations
International Journal of Dairy Technology
Lipid metabolism and biosynthesis
1.47
article

Comparative analysis of milk fat globule membrane proteins between porcine and human colostrum by a label‐free proteomics approach

Huiwen Zhao, Xiqing Yue, Wanying Song, Zhenghan Zhang, Xiaoyu Liu, Jiantao Li, Xianjun Liu
article en
5 citations

Abstract

This study aimed to investigate the similarities and differences in milk fat globule membrane (MFGM) proteins from porcine colostrum (PC) and human colostrum (HC) based on a label‐free proteomics approach. In total, 3901 and 4027 MFGM proteins were identified in PC and HC, respectively, including 3452 common proteins. Similar biological functions and pathways were found in two groups, whereas the quantities and types of MFGM proteins involved were different. This study compared the differences between MFGM proteins in PC and HC, effectively expanding the MFGM proteome and its bioinformatic database and providing new insights for the exploration of porcine milk.

International Journal of Dairy TechnologyVol. 77(4)
Shenyang Agricultural University (CN), General Hospital of Shenyang Military Region (CN)
Distinguished Professor of Liaoning Province
Openalex Percentile: Top 19%
Lipid metabolism and biosynthesis
1.47
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