Association of rs8670 Polymorphism in the MSX1 Gene With Non-Syndromic Cleft Lip With or Without Cleft Palate in Malay Population

Our data showed a lower incidence of the <i>rs8670: C>T</i> polymorphism among NSCL±P cases compared to control in this Malay population. However, since this variant is located in the 3'UTR, it could potentially impact the stability of <i>MSX1</i> mRNA.

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Publication Details

Journal
Cureus
Published
2024-09-08
DOI
https://doi.org/10.7759/cureus.68958
Primary Topic
Cleft Lip and Palate Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Association of rs8670 Polymorphism in the MSX1 Gene With Non-Syndromic Cleft Lip With or Without Cleft Palate in Malay Population

Zainul Ahmad Rajion, Bin Alwi Zilfalil, Saidi Jaafar, Roslina Rashid
Cureus
Cleft Lip and Palate Research
article

Association of rs8670 Polymorphism in the MSX1 Gene With Non-Syndromic Cleft Lip With or Without Cleft Palate in Malay Population

Zainul Ahmad Rajion, Bin Alwi Zilfalil, Saidi Jaafar, Roslina Rashid
article en

Abstract

Our data showed a lower incidence of the <i>rs8670: C>T</i> polymorphism among NSCL±P cases compared to control in this Malay population. However, since this variant is located in the 3'UTR, it could potentially impact the stability of <i>MSX1</i> mRNA.

CureusVol. 16(9)
Universiti Sains Malaysia (MY), International Islamic University Malaysia (MY), Hospital Universiti Sains Malaysia (MY)
Kementerian Sains, Teknologi dan Inovasi, Ministério da Ciência, Tecnologia e Inovação, Universiti Sains Malaysia
Zero hunger
Openalex Percentile: Top 83%
Cleft Lip and Palate Research
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