Diffuse Large B‐Cell Lymphoma in a Cynomolgus Monkey
A captive 17-year-old male cynomolgus monkey (Macaca fascicularis) developed diffuse large B-cell lymphoma (DLBCL). This was the first report of DLBCL presenting with a mandible mass and violation of the paranasal sinus in a cynomolgus monkey. The neoplasm showed marked microscopical malignant aspects. Immunohistochemical staining showed strong positive expression of CD20. These features may contribute to the diagnosis and therapeutics of DLBCL in NHPs.
Authors
- Hong Wang (ORCID: https://orcid.org/0009-0004-6763-3168)
- Heling Li (ORCID: https://orcid.org/0009-0000-8264-8529)
- Xinglong Chen (ORCID: https://orcid.org/0000-0003-2283-7293)
- Baohong Tian
- Zhi‐Gang Chen (ORCID: https://orcid.org/0000-0002-9309-7993)
- Long Zhang (ORCID: https://orcid.org/0000-0001-8139-0474)
- Deli Liu (ORCID: https://orcid.org/0000-0003-4513-5753)
- Qing Ning
- Faliang Zong
Institutions
- Kunming University of Science and Technology (CN)
- Yunnan Yingmao Biotechnology (China) (CN)
Publication Details
- Journal
- Journal of Medical Primatology
- Published
- 2024-09-08
- DOI
- https://doi.org/10.1111/jmp.12734
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00