A single exposure to brivaracetam or perampanel does not cause cell death in neonatal rats
Our results suggest that BRV and PER may have a positive safety profile-at least with respect to acute induction of cell death - and therefore may offer a safer option for the treatment of early life seizures.
Authors
- Anjik Ghosh
- Eric Witherspoon (ORCID: https://orcid.org/0000-0001-5593-4554)
- Marko Čuljat (ORCID: https://orcid.org/0000-0002-9021-1498)
- Patrick Alexander Forcelli (ORCID: https://orcid.org/0000-0003-1763-060X)
- Nicholas Zuczek (ORCID: https://orcid.org/0000-0001-5243-7544)
- Gabrielle Williams (ORCID: https://orcid.org/0000-0001-8670-2326)
- Suhasini Kaushal
- B. Bernstein
Institutions
- Georgetown University (US)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2024-09-09
- DOI
- https://doi.org/10.3389/fped.2024.1441891
- Citations
- 1
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.41