Cost-effectiveness of first-line enfortumab vedotin in addition to pembrolizumab for metastatic urothelial carcinoma in the United States

From the perspective of US payers, at a willingness-to-pay threshold of $150,000 per QALY, the combination of EV and pembrolizumab is estimated to not be cost-effective compared to traditional chemotherapy in the first-line treatment of mUC patients.

Authors

Institutions

Publication Details

Journal
Frontiers in Immunology
Published
2024-09-09
DOI
https://doi.org/10.3389/fimmu.2024.1464092
Citations
12
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
Field-Weighted Citation Impact
6.87

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article

Cost-effectiveness of first-line enfortumab vedotin in addition to pembrolizumab for metastatic urothelial carcinoma in the United States

Ouyang Xie, Long Wang, Heng Xiang, Chongqing Tan et al.
12 citations
Frontiers in Immunology
Bladder and Urothelial Cancer Treatments
6.87
article

Cost-effectiveness of first-line enfortumab vedotin in addition to pembrolizumab for metastatic urothelial carcinoma in the United States

Ouyang Xie, Long Wang, Heng Xiang, Chongqing Tan, Andong Li, Kehui Meng, Meiyu Wu, Xiaomin Wan
article en
12 citations

Abstract

From the perspective of US payers, at a willingness-to-pay threshold of $150,000 per QALY, the combination of EV and pembrolizumab is estimated to not be cost-effective compared to traditional chemotherapy in the first-line treatment of mUC patients.

Frontiers in ImmunologyVol. 15
Central South University (CN), Second Xiangya Hospital of Central South University (CN), Third Xiangya Hospital (CN)
Health Commission of Hunan Province, National Natural Science Foundation of China, Central South University, Natural Science Foundation of Hunan Province, Fundamental Research Funds for the Central Universities, Fundamental Research Funds for Central Universities of the Central South University
Openalex Percentile: Top 2%
Bladder and Urothelial Cancer Treatments
6.87
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Cost-effectiveness of first-line enfortumab vedotin in addition to pembrolizumab for metastatic urothelial carcinoma in the United States — Ouyang Xie, Long Wang, et al. · Frontiers in Immunology (2024) | TGRS Research Map | TGRS