From proteome to pathogenesis: investigating polycystic ovary syndrome with Mendelian randomization analysis
Overall, three protein-coding genes (<i>CDCP1</i>, <i>GLRX2</i>, and <i>KIRREL2</i>) may be related to a higher PCOS risk, suggesting that they may be entry points for exploration of PCOS pathogenesis and treatment, warranting further clinical investigations.
Authors
- Jiaqi Zhang (ORCID: https://orcid.org/0000-0002-3417-1508)
- Yuqing Li (ORCID: https://orcid.org/0000-0002-3410-6300)
- Jingmin Wang (ORCID: https://orcid.org/0000-0001-5157-7262)
- Aixia Gong (ORCID: https://orcid.org/0000-0003-0427-3674)
Institutions
- Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-09-09
- DOI
- https://doi.org/10.3389/fendo.2024.1442483
- Citations
- 1
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.54