Mechanical impact of regional structural deterioration and tissue-level compensation on proximal femur trabecular bone
Trabecular bone in low bone mass regions is more affected by bone mass loss. Structural deterioration primarily reduces bone strength, but improvements in tissue-level properties can mitigate this effect, especially in early osteoporosis. Targeted assessments and interventions are crucial for effective management. Future research should explore heterogeneous deterioration models to better understand osteoporosis progression.
Authors
- Chenglong Feng (ORCID: https://orcid.org/0009-0003-1682-8793)
- Shi Zhan (ORCID: https://orcid.org/0000-0002-5023-6789)
- Yuxiong Gan (ORCID: https://orcid.org/0000-0003-4237-7618)
- Wenxin Niu (ORCID: https://orcid.org/0000-0003-1349-4524)
- Ke Zhang (ORCID: https://orcid.org/0000-0001-6777-6290)
- Xinhao Xiang
Institutions
- Tongji University (CN)
- Shanghai Sixth People's Hospital (CN)
- Shanghai Sunshine Rehabilitation Center (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2024-09-09
- DOI
- https://doi.org/10.3389/fbioe.2024.1448708
- Citations
- 2
- Primary Topic
- Orthopaedic implants and arthroplasty
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation