Ultrasound assisted versus landmark based intrathecal administration of nusinersen in adults with spinal muscular atrophy disease: <scp>A</scp> randomized trial
In SMA adults, US assistance reduces the number of needle redirections needed for intrathecal drug administration. These results suggest that the US assistance may be advantageous for nusinersen therapy to reduce the therapeutic burden of intrathecal infusion.
Authors
- Gaetano Draisci (ORCID: https://orcid.org/0000-0003-0148-5073)
- Stefano Catarci (ORCID: https://orcid.org/0000-0002-3466-6527)
- Francesco Vassalli (ORCID: https://orcid.org/0000-0001-5067-9427)
- Mario Sabatelli (ORCID: https://orcid.org/0000-0001-6635-4985)
- Luciano Frassanito (ORCID: https://orcid.org/0000-0001-6406-2591)
- Eugenio Maria Mercuri (ORCID: https://orcid.org/0000-0002-9851-5365)
- Agata Katia Patanella
- Marika Pane (ORCID: https://orcid.org/0000-0002-4851-6124)
- Bruno Antonio Zanfini (ORCID: https://orcid.org/0000-0003-1312-5382)
- Mariangela Di Muro (ORCID: https://orcid.org/0000-0002-1070-4955)
- Matteo Biancone
- Eleonora Rizzi (ORCID: https://orcid.org/0009-0002-1989-5839)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Istituto Giannina Gaslini (IT)
- Agostino Gemelli University Polyclinic (IT)
- Centro Clinico Nemo (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Muscle & Nerve
- Published
- 2024-09-08
- DOI
- https://doi.org/10.1002/mus.28248
- Primary Topic
- Neurogenetic and Muscular Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Biogen