KEAP1-mutant atypical meningioma: illustrative case

To the authors' knowledge, this is the first report of KEAP1-mutant meningioma, including its clinical course after comprehensive management. Notably, treatment included multimodal radiotherapy with IMRT followed by SRS. SRS led to an excellent treatment response at the 7-month follow-up. However, radiation necrosis developed after both radiotherapy treatments, suggesting that radiological modification can be beneficial in patients with KEAP1 mutations. https://thejns.org/doi/10.3171/CASE24387.

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Publication Details

Journal
Journal of Neurosurgery Case Lessons
Published
2024-09-09
DOI
https://doi.org/10.3171/case24387
Citations
2
Primary Topic
Semiconductor materials and devices
Type
article
Field-Weighted Citation Impact
0.42
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article

KEAP1-mutant atypical meningioma: illustrative case

Armine T. Tayag, Elham Rahimy, Steven D. Chang, Amit Persad et al.
2 citations
Journal of Neurosurgery Case Lessons
Semiconductor materials and devices
0.42
article

KEAP1-mutant atypical meningioma: illustrative case

Armine T. Tayag, Elham Rahimy, Steven D. Chang, Amit Persad, Yusuke S. Hori, Sara Coleman Emrich, Jae‐Hyun Park, Gordon Li, Louisa Ustrzynski, Paul M Harary
article en
2 citations

Abstract

To the authors' knowledge, this is the first report of KEAP1-mutant meningioma, including its clinical course after comprehensive management. Notably, treatment included multimodal radiotherapy with IMRT followed by SRS. SRS led to an excellent treatment response at the 7-month follow-up. However, radiation necrosis developed after both radiotherapy treatments, suggesting that radiological modification can be beneficial in patients with KEAP1 mutations. https://thejns.org/doi/10.3171/CASE24387.

Journal of Neurosurgery Case LessonsVol. 8(11)
Stanford University (US)
Good health and well-being
Openalex Percentile: Top 38%
Semiconductor materials and devices
0.42
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KEAP1-mutant atypical meningioma: illustrative case — Armine T. Tayag, Elham Rahimy, et al. · Journal of Neurosurgery Case Lessons (2024) | TGRS Research Map | TGRS