Green Synthesis of ZnO Nanoparticles from <i>Dysoxylum binectariferum</i> Fruit Extract and Assessment of Antimicrobial Potential

Abstract The current investigation focuses on producing zinc oxide nanoparticles (ZnO NPs) utilizing a quick, economical, and environmentally friendly approach employing aqueous fruit extracts of Dysoxylum binectariferum plant. The ZnO NPs were thoroughly characterized using P‐XRD, FTIR, SEM, EDS, and BET techniques. The synthesized nanoparticles’ anti‐bacterial properties were evaluated against Gram‐negative bacteria ( E. coli and P. aeruginosa ) and Gram‐positive bacteria ( S. aureus and S. pyogenes ). The findings indicated that the synthesized material exhibited greater efficacy against Gram‐negative bacterial infections, especially E. coli . Furthermore, the anti‐fungal activity was examined using the C. albicans strain, demonstrating that the synthesized ZnO NPs were twice as effective against C. albicans compared to the conventional medication Griseofulvin. In contrast, Griseofulvin, with a 500 μM MIC against the C. albicans pathogenic fungal strain, did not display the same level of efficacy.