ThP8.4 - Initial Results of CAC (Cyanoacrylate Closure) of lower limb truncal venous incompetence

Abstract Aims We have tried CAC in our unit, as an emerging new treatment. We present our initial experience on efficacy and safety of the technique. Methods Venous trunks were treated with n-butyl Cyanoacrylate (Variclose® by biolas) as per IFU. Clinical and doppler US follow-up at three months was carried out. Data was captured prospectively. Results Eighty-six venous trunks (79 GSV, 5 SSV, 2 ATV) in 82 limbs of 65 patients were treated. Median length/ diameter of LSV treated was 32 /0.7 cms; 15/5 cms for SSV. Median volume of glue used was 1.83 mls. Eighty-two out of eighty-six (96%) trunks were successfully treated with complete primary occlusion. Four(4.5%) trunks did not demonstrate total occlusion at primary treatment. There was no extension of thrombus into deep veins and no immediate adverse reactions. On doppler US at 3 months, 58(70.7%) trunks demonstrated total occlusion. Twenty-four (29.3%) trunks were only partially occluded. which were deemed not suitable for thermal endovenous treatment. Nine (11%) patients had adverse events. One had pulmonary embolism two days after treatment. Five limbs developed erythema and swelling in the thigh which took few weeks to settle. Two patients had exaggerated thrombophlebitis of the treated GSV requiring hospital admission. Conclusion There is a high rate of primary occlusion of the treated trunk which does not appear to be maintained at short term follow up. There is glue associated adverse reactions and potential serious complications. It may limit the options of subsequent treatment where the glue treatment has not been successful.