Heat shock transcription factor 1 facilitates liver cancer progression by driving super‐enhancer‐mediated transcription of <scp>MYCN</scp>
The HSF1-MYCN axis constitutes a transcription-dependent regulatory mechanism that may function as both a prognostic indicator and a promising therapeutic target in liver cancer. Further exploration of this axis could yield valuable insights into novel treatment strategies for HCC.
Authors
- Xianghuo He (ORCID: https://orcid.org/0000-0001-8872-668X)
- Qili Shi
- Zhiao Chen (ORCID: https://orcid.org/0000-0003-4105-8674)
- Yizhe Liu (ORCID: https://orcid.org/0000-0001-5312-1584)
- Yue Su (ORCID: https://orcid.org/0009-0005-9731-9011)
Institutions
- Fudan University Shanghai Cancer Center (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/cam4.70157
- Citations
- 5
- Primary Topic
- Heat shock proteins research
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- National Natural Science Foundation of China
- Fudan University