EP609 - Factors affecting the recurrence rate of acute uncomplicated diverticulitis: Single-center experience

Abstract Introduction Acute diverticulitis (AD) is a prevalent condition, and the use of antibiotics for uncomplicated cases remains a topic of debate. Understanding the risk factors for recurrence is crucial for guiding treatment strategies. This study aimed to investigate the risk factors for recurrence within one year following hospital admission for AD. Methods A retrospective analysis of patients admitted to a District General Hospital (DGH) with acute diverticulitis in 2022 was conducted. The study examined patient demographics, initial observations, admitting investigations, care methods, and recurrence within a year. Statistical analysis was performed using SPSS 22 and the Chi-square test. Results The results revealed that out of 105 patients, 39 (37.1%) experienced a recurrence within a year. Notably, age, gender, and diabetes did not significantly impact recurrence (P=0.2,0.06,0.6 respectively), while a history of previous diverticulitis and white cell count (WCC) between 10-15 were associated with higher recurrence rates (P=0.032,0.011 respectively). Furthermore, Hinchey grade, use of antibiotics, and the method of care, whether ambulatory or inpatient, did not show significant differences in recurrence rates (P=0.5,0.8,0.92 respectively). Surgical intervention or interventional radiology (IR) drainage also did not affect the occurrence of recurrence (P=0.91,0.92, respectively). Conclusion The findings suggest that the use of antibiotics for uncomplicated AD may not reduce the risk of recurrence. Additionally, a history of previous admission with AD and elevated WCC were identified as significant risk factors for recurrence within one-year post-hospitalization. However, age, gender, diabetes, Hinchey grade, and interventions did not demonstrate statistical significance in predicting recurrence.