Synthesis of Novel Sulfonamide Derivatives Featuring 1-(Methylsulfonyl)-4-(2,3,4-Trimethoxybenzyl)Piperazine Core Structures
Herein we report the synthesis of three novel sulfonamide derivatives of trimetazidine—medication primarily used to treat angina pectoris. The new compounds have been fully characterized with their melting point, 1H- and 13C-NMR, UV, and mass spectrometry. The collected data confirm the successful synthesis and structural integrity of the new molecules.
Authors
- Iliyan Ivanov (ORCID: https://orcid.org/0000-0002-4662-3735)
- Diyana Dimitrova (ORCID: https://orcid.org/0009-0009-2623-0043)
- Dimitar G. Bojilov (ORCID: https://orcid.org/0000-0001-6569-8348)
- Stanimir P. Manolov (ORCID: https://orcid.org/0000-0002-0314-6553)
- Paraskev T. Nedialkov (ORCID: https://orcid.org/0000-0001-5640-6120)
Institutions
- Plovdiv University (BG)
- Medical University of Sofia (BG)
Publication Details
- Journal
- Molbank
- Published
- 2024-09-09
- DOI
- https://doi.org/10.3390/m1879
- Primary Topic
- Phenothiazines and Benzothiazines Synthesis and Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00