Microbial Heterogeneity Identification of Cerebral Thrombi Via Metagenomic Next‐Generation Sequencing‐Based Strategy
This study, based on the approach of metagenomic next-generation sequencing, provides a diagnostic microbiological method to discriminate individuals with cardioembolic thrombi from those with large-artery atherosclerosis thrombi with human cerebral thrombi samples. Our findings provide a fresh perspective on microbial heterogeneity of cerebral thrombi and demonstrate biological processes and pathway features of cerebral thrombi.
Authors
- Yuxuan He (ORCID: https://orcid.org/0009-0008-5324-6051)
- Zhenhua Zhou (ORCID: https://orcid.org/0000-0002-4548-4489)
- Huan Xu (ORCID: https://orcid.org/0000-0001-5861-0707)
- Xingtong Li
- Linke Zhou (ORCID: https://orcid.org/0009-0001-9933-4312)
- Meiling Jiang (ORCID: https://orcid.org/0000-0001-9985-3510)
- Min Wu (ORCID: https://orcid.org/0000-0003-4485-975X)
- Xi Chen (ORCID: https://orcid.org/0000-0003-0248-8161)
- Li Chen (ORCID: https://orcid.org/0000-0002-9650-497X)
- Li Gui (ORCID: https://orcid.org/0000-0002-7841-7223)
- Jing Li (ORCID: https://orcid.org/0000-0001-8375-7890)
Institutions
- Army Medical University (CN)
- Vision Medicals (China) (CN)
- Southwest Hospital (CN)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2024-09-09
- DOI
- https://doi.org/10.1161/jaha.123.033221
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- National Natural Science Foundation of China